Parabens – new research on links to breast cancer

There has been a lot of discussions about parabens in products, and if they are safe or not. Today, many product companies has chosen to take them away, as there are more and more research showing that they can cause a multitude of diseases. A Paraben is a preservative and this then has to be replaced by something else that keeps the product from going off, it is often replaced by phenoxyethanol, which is not all that much better, but consumers today have not yet been used to look out for this ingredient as well.

All we can say, is that read what is on the products that you use, if there is something on there that you do not understand, google it!

 

Here is the research article!

//Anna

Parabens in Breast Tissue not Limited to Women who Have Used Underarm Products New research into the potential link between parabens and breast cancer has found traces of the chemicals in breast tissue samples from all of the women in the study. Parabens are commonly used as preservatives in cosmetics, food products and pharmaceuticals. As the research shows that parabens are measurable in the tissue of women who do not use underarm cosmetics the parabens must enter the breast from other sources.

Breast tissue samples were taken from 40 women, with the results showing that all of the women had at least one paraben in their tissue. The research, published in the Journal of Applied Toxicology, was a collaborative study led by Dr Philippa Darbre, University of Reading and Mr Lester Barr, University Hospital of South Manchester.

The research team studied tissue samples from 40 women undergoing mastectomies between 2005 and 2008 for first primary breast cancer in England. In total, 160 samples were collected, four from each woman, covering serial locations from the axilla (nearest the armpit) to the sternum (breast bone). 99% of the tissue samples contained at least one paraben and 60% of the samples had five.

A number of studies since 1998 have raised concerns about the potential role of parabens in breast cancer as these chemicals possess oestrogenic properties and oestrogen is known to play a central role in the development, growth and progression of breast cancer. In particular, a link was proposed between the disproportionate incidence of breast cancer in the upper outer quadrant of the breast and oestrogenic chemicals in that region, maybe from local application of underarm cosmetic products.

“Our study appears to confirm the view that there is no simple cause and effect relationship between parabens in underarm products and breast cancer” said Mr Lester Barr, consultant surgeon at the University Hospital of South Manchester and Chairman of the Genesis Breast Cancer Prevention Appeal, which part sponsored the study.

“The intriguing discovery that parabens are present even in women who have never used underarm products raises the question: where have these chemicals come from?”

Key findings of the study included:

• One or more paraben esters were detected in 158 of the 160 samples studied (99%) and 96 of the samples (60%) contained all five of the most common paraben esters.

• The overall median value for total parabens in the breast tissue was 85.5 ng/g – one billionth of a gram of parabens per gram of breast tissue – ranging from 0 ng/g to 5134.5 ng/g. This level was four times higher than the 20.6 ng/g recorded by a smaller study in 2004.

• Overall median values for the individual parabens were highest for n- propylparaben (16.8 ng/g) and methylparaben (16.6 ng/g), with lower levels for n- butylparaben (5.8 ng/g), ethylparaben (3.4 ng/g) and isobutylparaben (2.1 ng/g).

• There was a disproportionate incidence of breast cancer in the upper outer quadrant nearest the armpit and significantly higher levels of n-propylparaben were detected in the axilla region, closest to the armpit, than in the mid or medial regions. The other four parabens were equally distributed across all parts of the breast.

“The fact that parabens were detected in the majority of the breast tissue samples cannot be taken to imply that they actually caused breast cancer in the 40 women studied,” said Dr Philippa Darbre, Reader in Oncology at the University of Reading, who also led the 2004 study. “However, the fact that parabens were present in so many of the breast tissue samples does justify further investigation.”

This paper is published in the Journal of Applied Toxicology. To request a media copy contact Lifesciencenews@wiley.com or +44 (0) 1243 770 375

Advertisements

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out / Change )

Twitter picture

You are commenting using your Twitter account. Log Out / Change )

Facebook photo

You are commenting using your Facebook account. Log Out / Change )

Google+ photo

You are commenting using your Google+ account. Log Out / Change )

Connecting to %s